Introduction:
The relationship between strep infections and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) has long intrigued the medical community. This blog delves into the current understanding of this link and how we address it at Mind Align Psychiatry.
What is PANDAS?
PANDAS is a subset of Pediatric Acute-onset Neuropsychiatric Syndrome (PANS). It is characterized by a sudden onset of obsessive-compulsive disorder (OCD) and tic disorders, which are believed to be triggered by Group A beta-hemolytic streptococcal (GABHS) infections.
The Complex Relationship:
The connection between streptococcal infections and neuropsychiatric disorders like PANDAS is intricate. Diagnosing PANDAS often involves ruling out other neurological and psychiatric conditions.
Biological Markers:
The diagnosis can involve laboratory tests such as anti-streptolysin O (ASO) and anti-deoxyribonuclease B (anti-DNAse B) titers. Elevated levels of these markers are more commonly observed in PANDAS compared to PANS, underscoring their significance in diagnosis.
Pathophysiology:
A leading theory suggests that antibodies formed against streptococcal proteins might mistakenly target brain proteins, especially in the basal ganglia, precipitating rapid-onset OCD symptoms.
Treatment:
In cases of PANDAS, antibiotic therapy is often used, though its effectiveness in improving OCD and tic symptoms is still under investigation.
Discover Wellness with Mind Align Psychiatry:
At Mind Align Psychiatry, we believe in a holistic and personalized approach to mental health care. One of the many innovative options we explore to provide effective solutions for condition like PANDAS. Begin your journey towards a healthier and more balanced life by visiting www.mindalignpsych.com or texting or calling 484-799-9211.
