In the quest for effective treatments for complex mental health conditions like treatment-resistant OCD and anxiety, Amantadine, an antiviral medication, has emerged as a noteworthy supplementary option. At Mind Align Psychiatry, we're dedicated to exploring such innovative treatments to offer comprehensive care.
Amantadine's Role in Treating OCD and Anxiety:
Originally used to treat the flu, Amantadine has shown potential in improving symptoms of OCD, anxiety, ADHD, and disruptive mood dysregulation disorder. Its off-label use in OCD treatment is due to its promising effects, despite the lack of extensive double-blind studies for FDA approval.
Mechanism of Action:
- Amantadine's effectiveness in OCD and anxiety predominantly arises from its inhibition of NMDA receptors and its ability to stabilize the glutamatergic system, along with neuroprotective properties.
- Supplementary Use with SSRIs: Amantadine has demonstrated benefits when used as a supplement with SSRIs, specifically showing improvements on the Yale-Brown Obsessive Compulsive Scale (Y-BOCS).
- Recommended Dosage: The typical dosing for OCD is around 100 mg/day.
- Study Reference: For more detailed information, a relevant study can be found here: https://bit.ly/3S9ngM9
Additional Benefits of Amantadine:
Apart from OCD and anxiety, Amantadine has shown efficacy in improving depression symptoms and enhancing neuroplasticity, particularly in individuals with brain injuries. Its safety profile suggests it is suitable for long-term use.
Common Side Effects:
Generally, Amantadine is better tolerated than stimulants, with milder side effects such as decreased appetite and insomnia. Caution is advised for individuals with reduced kidney function or glaucoma due to potential anticholinergic effects.
Amantadine and Viral Vaccines:
As an antiviral medication, Amantadine should be paused during the administration of live attenuated vaccines to ensure vaccine efficacy.
Discover Wellness with Mind Align Psychiatry:
At Mind Align Psychiatry, we believe in a holistic and personalized approach to mental health care. Amantadine represents just one of the many innovative options we explore to provide effective solutions for conditions like OCD and anxiety. Begin your journey towards a healthier and more balanced life by visiting www.mindalignpsych.com or texting or calling 484-799-9211.
